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Synvisc One

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Synvisc One

What is SYNVISC?

Synvisc One is a viscosupplement injection that supplements the fluid in your knee to help lubricate and cushion the joint, and can provide up to six months of osteoarthritis knee pain relief with three injections.

When should I consider SYNVISC?

SYNVISC is for people with knee osteoarthritis who have not received enough pain relief from diet, exercise and over-the-counter pain medication. If you’ve tried these options and are still feeling knee pain, tell your doctor and ask if SYNVISC or Synvisc-One® (hylan G-F 20) could help.

How is SYNVISC given?

SYNVISC is typically provided by a specialist such as an orthopaedic surgeon or rheumatologist. It is injected directly into the knee over the course of three doctor visits, one week apart.

Is SYNVISC covered by insurance?

SYNVISC is covered by Medicare and most insurance plans. If you have been denied coverage click here.

What are the side effects of SYNVISC?

In studies, about 7% of patients experienced pain, swelling and/or fluid buildup around the knee. Other side effects, such as rash, have been reported rarely.

What is the procedure like?

Each injection takes a few minutes and can be done in your doctor’s office. To watch a video of a real patient’s injection with This product,

Will the injections hurt?

Your doctor will likely apply a numbing agent before your SYNVISC injections.

What happens after the injections?

It is recommended you avoid strenuous activities (for example, high-impact sports such as tennis or jogging) or prolonged weight-bearing activities for approximately 48 hours following each injection. You should consult your doctor regarding the appropriate time to resume these activities.

When will I start to feel pain relief?

Some patients may begin to feel osteoarthritis knee pain relief after the first injection, but you need to have all three injections to get the maximum benefit. Although everyone responds differently, most patients feel the greatest relief 8 to 12 weeks after the first injection.

How long will I experience knee pain relief?

Although all patients respond differently, your osteoarthritis knee pain relief can last up to six months.

Can I receive This product treatment more than once?

Yes, This product can be repeated safely. When your osteoarthritis knee pain returns, talk to your doctor to see whether This product is right for you.

Can both my knees be treated with This product?

Yes. You can receive treatment in both knees at the same time or at different times. Ask your doctor what is best for you.

What is This product made from?

The injection contains a gel-like mixture made from a substance called hyaluronan (pronounced hy-al-u-ROE-nan) that comes from chicken combs. Hyaluronan is a natural substance found in the body and is present in very high amounts in joints. The body’s own hyaluronan acts like a lubricant and a shock absorber in the joint and is needed for the joint to work properly.

How is SYNVISC different from Synvisc-One?

This product is the same formulation as Synvisc-One. The only difference is that This product is provided with one injection, compared to the three injections required for This product. Both treatments can provide up to six months of osteoarthritis knee pain relief.
Get a quick overview of This product.
Indication

Synvisc-One® (hylan G-F 20) is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen.
Important Safety Information for Synvisc-One

Before trying This product, tell your doctor if you have had an allergic reaction, such as swelling of the face, tongue or throat, respiratory difficulty, rash, itching or hives to SYNVISC or any hyaluronan-based products. Allergic reactions, some which can be potentially severe, have been reported during the use of Synvisc-One. Should not be used in patients with an infected knee joint, skin disease or infection around the area where the injection will be given, and should be used with caution when there is swelling of the legs due to problems with venous stasis or lymphatic drainage.

This product is only for injection into the knee, performed by a doctor or other qualified health care professional. This producte has not been tested to show pain relief in joints other than the knee. Tell your doctor if you are allergic to products from birds – such as feathers, eggs or poultry – or if your leg is swollen or infected.

This product has not been tested in children (≤21years old), pregnant women or women who are nursing. You should tell your doctor if you think you are pregnant or if you are nursing a child.

Talk to your doctor before resuming strenuous weight-bearing activities after treatment.

The side effects sometimes seen after Synvisc-One include (<2% each): pain, swelling, heat, redness, and/or fluid build-up in or around the knee. Tell your doctor if you experience any side effects after treatment with Synvisc-One.

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